proteoglycan相关论文
目的:探讨大鼠骨髓间充质干细胞（BMSCs）来源的外泌体对髁突软骨细胞蛋白多糖含量表达的影响，为骨关节病的防治提供基础。方法:研究时......
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Hsa-miR-15aprotectsagainstosteoarthritisbytargetingaggrecanase-2(ADAMTS5)inhumanchondrocyt
Objective:Toinvestigatetheexpressionandroleofhas-miR-15ainosteoarthritis(OA),aswellastheassociatedmechanism.......
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Esophageal squamous cell carcinoma(ESCC)is a highly malignant disease that has a poor prognosis.Its high lethality is ma......
The Effects of Nivalenol on Proteoglycan Catabolism, Oxidative Stress and Chondrocyte Apoptosis in B
Mycotoxin contamination is one of the risk factors for Kashin-Beck Disease (KBD), and nivalenol is a member of the trich......
本实验对6例新生儿椎间盘的髓核和纤维环中的生化成分进行了研究.结果表明髓核中糖醛酸、半乳糖胺、总己糖胺的含量明显高于纤维环......
肾小球系膜细胞和细胞外基质(extra-cellular matrix,ECM)是肾小球重要的结构和功能单位。肾小球基底膜是特殊的ECM,它主要由IV型......
With high water content(～90 wt%) and significantly improved mechanical strength(～MPa),double network(DN) hydrogels have em......
The extracellular matrix is a diverse composition of glycoproteins and proteoglycans found in all cellular systems.The e......
A disintegrin and metalloproteinase with thrombospondin motif 1(ADAMTS1) expression increases in acu
Acute aortic dissection(AAD) is a life-threatening cardiovascular disease caused by progressive medial degeneration of t......
In the presence of danger:the extracellular matrix defensive response to central nervous system inju
Glial cells in the central nervous system (CNS) contribute to formation of the extracellular matrix, which provides adhe......
[目的]探讨JNK及P38信号分子在周期性张应变下调椎间盘纤维环细胞蛋白多糖-aggrecan mRNA表达中的作用.[方法]采用自制周期性张应......
Objective To investigate the histological viability and the biochemical change of fresh allografted intervertebral disc ......
Light deprivation is known to induce a significant decrease in the percentage of N-methyl-D-aspartate receptor 2A subuni......
Aim:To have a better understanding of the expression and regulation of versicanisoforms in neural precursor cells (NPC)......
NG2细胞是新发现的一类广泛存在于成熟和发育期中枢神经系统的胶质细胞群体。这些细胞表面表达NG2硫酸软骨素蛋白多糖,因而常被称......
Currently, hepatitis B virus(HBV), upon attaching to human hepatocytes, is considered to interact first with heparan sul......
Ethanolic extracts of babandotan leaves(Ageratum conyzoides L.) prevents inflammation and proteoglyc
Objective:To analyze the effects of Ageratum conyzoides L.on the monosodium iodoacetate induced osteoarthritis rats.Meth......
Kashin- Beck Disease (KBD) is an endemicchronic osteoarthropathy affecting about2 .5mil-lion residents with over30 milli......
Objective:To observe the regulative effects of Salvia Miltiorrhiza injection on rabbit articular chondrocytes apoptosis ......
Glypican-3(GPC3)is a cell surface oncofetal proteoglycan that is anchored by glycosylphosphatidylinositol.Whereas GPC3 i......
Proteoglycans are a group of molecules that contain at least one glycosaminoglycan chain,such as a heparan,dermatan,chon......
The Cre-loxP system was introduced in theproduction of recombinant AAV (rAAV). Defective adenovi-rus AdLC was used as th......
CONSTRUCTING ADENO-ASSOCIATED VIRUS-TGFβ_3 AND COMPARING ITS BIOLOGICAL EFFECT ON PROTEOGLYCAN SYNTH
Objective To construct adeno-associated virus (AAV) expression system for transforming growth factor β3 (TGFβ3) and de......
目的:研究三角帆蚌蛋白多糖的基本特征。方法:运用分光光度比色法测量多糖和蛋白质含量,傅立叶变换红外光谱分析官能基团,高效液相......
Effect of Ermiao Recipe (二妙方)with Medicinal Guide Angelicae Pubescentis Radix on Promoting the Homin
Objective:To investigate the effect of Ermiao Recipe(二妙方,EMR)with medicinal guide Angelicae Pubescentis Radix(APR)on ......
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Diabetic nephropathy(DN),a long term complication of diabetes,is the most common cause of end-stage renal disease,increa......
Serglycin belongs to a family of small proteoglycans with Ser-Gly dipeptide repeats,and it is modified with different ty......
Silicosis is one of the most serious occupational diseases which affect many workers’ health in China. Under the guidan......
A proteoglycan with a molecular mass of 39810 as determined by gel filtration, was obtained from dry, powdered sclerotia......
,Glycosylation of dentin matrix protein 1 is critical for fracture healing via promoting chondrogene
Fractures are frequently occurring diseases that endanger human health.Crucial to fracture healing is cartilage formatio......
Characterization of a new monoclonal anti-glypican-3 antibody specific to the hepatocellular carcino
AIM To characterize the antigen on HepG2 cell that is specifically recognized by a new monoclonal antibody raised agains......
蛋白质是角膜基质的主要组成成分,由角膜上皮细胞、基质细胞、内皮细胞分泌到细胞外基质.SDS-聚丙烯酰胺凝胶分离技术和光谱测定技......
Extracellular matrix synthesis and ultrastructural changes of degenerative disc cells transfected by
Objective To determine whether the synthesis of proteoglycan, collagen and associated ultrastructure are related to the ......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
In the presence of danger:the extracellular matrix defensive response to central nervous system inju
Glial cells in the central nervous system (CNS) contribute to formation of the extracellular matrix, which provides adhe......
睾丸蛋白聚糖1（SPOCK1）是一种细胞外基质糖蛋白，能够抑制组织蛋白酶的活性及促进低亲和力钙的结合。 SPOCK1对哺乳动物的发育至关重要......
目的 观察小分子蛋白多糖decorin(DCN)局部注射对兔耳增生性瘢痕的抑制作用.方法 新西兰大白兔8只,建立增生性瘢痕动物模型,随机分......
Aggrecan is the major proteoglycan in the articular cartilage. This molecule is important in the proper functioning of a......
从枣中分离得到粗蛋白聚糖，经DEAE—Sepharose CL-6B、Sepharose CL-6B和Sephadex G-200柱层析，分离纯化得白色粉末状枣蛋白聚糖（ZSG4......
对家兔用胶原酶施行实验性髓核化学溶解术。结果表明,胶原酶注射后3周,腰椎间盘髓核(LNP)总胶原和可溶性胶原可增多,这似与组织损......
参照Ｈａｓｃａｌｌ实验方法建立了牛关节软骨体外培养，并通过组织学观察，３５Ｓ掺入率测定及已糖醛酸测定的方法证明在加入２０％小牛血清的ＤＭＥＭ培养液中，培养７ｄ后，软骨......
本文以成年大鼠脑组织为实验对象，应用层析、酶解及电泳技术对３种提取方法２种提取剂提取蛋白聚糖的效果进行分析比较。结果表明：①用４ｍｏｌ／Ｌ盐......
应用小牛关节软骨短期器官温育的方法,研究了谷胱甘肽(GSH)对Cu~(2+)-H_2O_2导致关节软骨蛋白聚糖(PG)降解的影响。结果表明:GSH能......
红枣作为药食同源植物，具有许多生理活性。对金丝小枣蛋白聚糖的提取纯化及其结构进行了研究。经DEAE—SepharoseCL-6B、SepharoseC......
Versican belongs to the family of the large aggregating chondroitin sulfate proteoglycans located primarily within the e......
